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27th Rhine-Knee Regional Meeting on Biocrystallography
25.-27. September 2013, Schluchsee
 
Sessions in Room Riesenbühl, breaks in room Bildstein
 
 Day 1: Wednesday, September 25, 2013
15:00 - 17:30
Registration  (lobby)
17:30 - 19:20
Welcome / Snack-buffet
19:20 - 19:30
Welcome address
19:30 - 21:30
19:30 - 19:45
 
 
19:45 - 20:00
 
 
20:00 - 20:15
 
20:15 - 20:30
 
 
20:30 - 20:45
 
 
20:45 - 21:30
 
Session 1 - Crystals
Designed armadillo-repeat proteins: Development of a modular peptide recognition. Simon Hansen (University of Zurich)
 
Engineering novel crystallization chaperones with tunable crystal packing and increased power of phasing. Alexander Batyuk (University of Zurich)
 
Improvement of crystal quality by seeding. Tobias Rumpf (University of Freiburg)
 
Analysing interfaces in protein crystals through evolution. Jose Duarte (Paul Scherrer Institute, Villigen)
 
Automated crystal harvesting using a wireless, mobile microrobot. David Sargent (ETH Zurich)
 
Perspective lecture
Macromolecular Crystallography at Synchrotrons. What's next? Thomas Schneider (EMBL c/o DESY, Germany)
from 21:30
Networking
 
 Day 2: Thursday, September 26, 2013
07:00 - 08:45
Breakfast
09:00 - 10:30
 
09:00 - 09:15
 
 
09:15 - 09:30
 
09:30 - 09:45
 
 
09:45 - 10:00
 
10:00 - 10:15
 
 
10:15 - 10:30
 
Session 2 - Membrane proteins
 
The structural basis of autotransporter translocation by TamA. Fabian Gruss (Biozentrum, Basel)
 
The nitrite channel NirC. Nikola Schwarzer (University of Freiburg)
 
The structure of NADH:ubiquinone oxidoreductase (NQR) from Vibrio cholera. Georg Vohl (University of Freiburg)
 
X-ray structure of mitochondrial complex I. Christophe Wirth (University of Freiburg)
 
Respiratory complex I: The steam engine of the cell? Stefan Steimle (University of Freiburg)
 
Crystallographic low-resolution imaging of membrane proteins. Vladimir Y. Lunin (Institute of Mathematical Problems of Biology RAS, Moscow)
10:30 - 11:00
Coffee Break
11:00 - 12:30
 
11:00 - 11:30
 
11:30 - 11:45
 
 
11:45 - 12:00
 
 
12:00 - 12:10
 
 
12:10 - 12:20
 
12:20 - 12:30
 
Session 3 - Data quality, data acquisition and structure determination
 
How good are my data really? Kay Diederichs (University of Konstanz)
 
On effective and optical resolution of diffraction data sets. Alexandre Urzhumtsev (IGBMC, Illkirch)
 
On the use of phosphorus for nucleic acid structure determination. Guanya Peng, (Swiss Light Source, Paul Scherrer Institute, Villigen)
 
Less is more – single photon counting data collection in the laboratory. Clemens-Schulze-Briese (DECTRIS, Baden)
 
What´s new at Rigaku? Alex Griffin (Rigaku, Sevenoaks)
 
Latest Developments in Home-Lab Crystallography from Bruker AXS. Vernon Smith, (Bruker AXS, Karlsruhe)
12:30 - 13:30
Lunch (picnic boxes, Bildstein)
14:00 - 17:00
Excursion (A: Brewery visit, B: Hiking)
Meeting point : Schluchsee  Hotel entrance
18:00 - 19:30
Dinner
19:45 - 21:30
 
19:45 - 20:00
 
 
20:00 - 20:15
 
 
20:15 - 20:30
 
 
20:30 - 20:45
 
 
20:45 - 21:00
 
 
21:00 - 21:15
 
 
 
21:15 - 21:30
 
Session 4 - Enzymes and post-translational modifications
 
Cytochromics – A systematic approach to multiheme proteins. Bianca Hermann (University of Freiburg)
 
Gene history inferred from protein structures – The evolution of GBD superfamily. Marc Bergdoll (IBMP, CNRS, Strasbourg)
 
Structural analysis of amidase AmiA from S. aureus and its substrate. Felix Büttner (University of Tübingen)
 
Structure and putative mechanism of chorismatase-FkbO. Juneja Puneet (University of Konstanz)
 
Fic-mediated adenylylation inhibits GyrB by interfering with ATP hydrolysis. Frédéric Stanger (Biozentrum, Basel)
 
Structural analysis of the glycosyltransferase of the bacterialtoxin PaTox – key player of a new inhibition mode of GTPase mediated signaling pathways. Xenia Bogdanovic (University of Freiburg)
 
Structural analysis of the antiviral ISGylation system. Anja Basters (University of Freiburg)
From 21:30
Networking
 
 Day 3: Friday, September 27, 2013
07:00 - 08:45
Breakfast
09:00 - 10:30
 
09:00 - 09:15
 
 
09:15 - 09:30
 
 
09:30 - 09:45
 
 
09:45 - 10:00
 
 
10:00 - 10:15
 
 
10:15 - 10:30
 
Session 5 - Structure-based drug design and ribosome
 
Molecular mechanism of action of microtubule targeting agents. Andrea Prota (Paul Scherrer Institute, Villigen)
 
Two targets for the price of one: inhibitor complexes of AR/AKR1B10. Francesc Xavier Ruiz (IGBMC, Illkirch)
 
Structural Research in Pharma. Alexander Pautsch (Boehringer Ingelheim Pharma, Biberach)
 
Impact of Fragments in Kinase Inhibitor Discovery – Beyond Growing and Linking. Andreas Kuglstatter (F. Hoffmann-La Roche AG)
 
Purification, characterization and crystallization of the human ribosome. Heena Khatter (IGBMC, Illkirch)
 
The basis of SRP receptor recruitment and GTPase activation by SRP RNA. Nikolaus Schmitz (ETH Zurich)
10:30-11:00
Coffee Break
11:00 - 12:25
 
11:00 - 11:30
 
 
 
11:30 - 11:55
 
11:55 - 12:10
 
 
12:10 - 12:25
 
Session 6 - XFEL and macromolecular complexes
 
Perspective lecture
The future of protein crystallography with SwissFEL. Gebhard F.X. Schertler (Paul Scherrer Institute, Villigen)
 
Structure determination via SFX. Karol Nass (MPI Medical Research, Heidelberg)
 
PAAR-repeat proteins sharpen and diversify the type 6 secretion system. Sergeii Buth (EPFL, Lausanne)
 
Structural basis of Coxsackievirus CVA24v cell attachment. Georg Zocher (University of Tübingen)
12:25 – 12:30
Concluding remarks
12:30 –14:00
Lunch
14:00
End of the meeting
 

 

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